The C-reactive protein to prealbumin ratio on admission and its relationship with outcome in patients hospitalized for acute heart failure

BackgroundInflammation and malnutrition are common problems in patients who hospitalized for acute heart failure (AHF). C-reactive protein (CRP) is an acute-phase reactant nonspecific marker evaluating systemic inflammation. There has been growing interest prealbumin nutritional assessment. Additionally, a negative because its synthesis suppressed the inflammatory setting which cytokines stimulate hepatic production of proteins (e.g. CRP). Therefore, CRP to ratio (CP ratio) may be comprehensive inflammation malnutrition. We evaluated relationship CP with mortality AHF.MethodsWe analyzed 257 AHF had levels examined on admission.ResultsThe median admission was 0.57, interquartile range 0.11 1.94. In receiver operating characteristic curve analysis, area under 0.729 optimal cut-off point all-cause death >1.60 (sensitivity: 67.5%; specificity: 77.6%; p = 0.003). Kaplan-Meier survival curves showed that high (>1.60) significantly greater risk all-cause, cardiac, non-cardiac (log-rank test, all p<0.001) than low (?1.60). Multivariable analysis adjusted imbalanced baseline variables independently associated higher (adjusted hazard 3.88; 95% confidence interval 1.91–7.86; p<0.001).ConclusionsThe two proteins, prealbumin, useful stratification AHF.